Duetact is a prescription medicine in tablet form that contains the active ingredients pioglitazone and glimepiride. It is used to manage type 2 diabetes by effectively lowering high blood sugar levels. By maintaining blood sugar control, Duetact helps reduce the risk of developing severe complications such as kidney damage, limb amputation, vision loss, neuropathy, and sexual dysfunction. This medication is also available under the brand names Pozitiv G, AMARYL P, and Pioglar G.